B-12 (Methylcobalamin) 1000mcg (Metabolics), 90 Capsules
- Brand: Metabolics
- Availability: In Stock
Vitamin B12 (Cobalamin) NOW 90 CAPSULE POT SIZE (formally 60 capsules) Needed to prevent anemia; aids folic acid in regulating formation of red blood cells; helps utilization of iron. Required for proper digestion, absorption of foods, synthesis of protein, metabolism of carbs and fats. Body can ...
Vitamin B12 (Cobalamin) NOW 90 CAPSULE POT SIZE (formally 60 capsules)
Needed to prevent anemia; aids folic acid in regulating formation of red blood cells; helps utilization of iron. Required for proper digestion, absorption of foods, synthesis of protein, metabolism of carbs and fats. Body can save up to 5 years’ worth of vitamin B12—strict vegetarians must remember to boost B12 intake, as this vitamin is found almost exclusively in animal tissues.
- Food containing Vitamin B12 is bound to animal proteins and needs to be freed. So when the food reaches the stomach it is split by an enzyme Pepsin (produced in the stomach only if sufficient amounts of Hydrochloric acid )
- The stomach also produces intrinsic factor (IF) , a protein that is needed later in the pathway.
- Other proteins known as R-Binders carry the B12 into the small intestine
- In the intestine, intrinsic factor (from the stomach ) attaches itself to the B12 and transports it to the last section of small intestine, the ileum. The cells lining the ileum contain receptors that grab onto the B12-Intrinsic factor complex and drag it into the blood stream
- In the bloodstream, another protein, transcobalamin2 carries the Vitamin B12 to all the cells in the body, transporting any extra to the liver for storage.
Methylcobalamin is the most natural form of B12 and needs noconverting. It is already in its “ready to use” form. Methylcobalamin is the active coenzyme form necessary for any biological activity. It also is the least stable with the shortest shelf life, converting back to hydroxycobalamin if not stored correctly. Methylcobalamin is sometimes referred to as “active B12” as it is in a form ready to be used by the cells.
What does Vitamin B12 do?
- It contributes to the reduction of tiredness and fatigue
- It contributes to normal energy yielding metabolism
- It contributes to normal functioning of the nervous system
- It contributes to normal red blood cell formation
- It has a role in the process of cell division
- It contributes to normal homocysteine metabolism
- It contributes to normal psychological function
- It contributes to normal functioning of the immune system
There is no one particular symptom that suggests a Vitamin B12 deficiency. Symptoms may depend on the age and genetic disposition of the individual, and also the length and severity of deficiency. Because Vitamin B12 has so many functions, including the health of nerves, brain, blood and immune system, as well as the formation of DNA, B12 deficiency can impair functioning in almost any part of the body. The following signs and symptoms are common symptoms of a Vitamin B12 deficiency but can also arise from other causes.
Mental changes include irritability, apathy, sleepiness, paranoia, personality changes, depression, memory loss, dementia, hallucinations, violent behaviour and in children developmental delay and/or autistic behaviour.
Neurological signs and symptoms include pain, tingling or numbness, decreased sense of touch, pain or temperature, weakness, loss of awareness of body position, clumsiness, tremor, symptoms mimicking Parkinsons disease or multiple sclerosis, spastic muscles, incontinence, paralysis, visual changes and damage to the optic nerve
Vascular changes include, transient ischaemic attacks (TIAs or mini strokes) CVA or stroke, coronary artery disease, heart attack, congestive heart failure, palpitations, low blood pressure when standing causing fainting, deep vein thrombosis (blood clot in the arm or leg) and pulmonary embolism.
Other signs and symptoms may include shortness of breath, generalized weakness, chronic fatigue or tiredness, loss of appetite and weight loss, epigastric pain (poor digestion, full or bloated feeling after eating normal or small meals), diarrhoea or constipation, increased susceptibility to infection, poor wound healing, failure of new born to thrive, tinnitus, vitiligo (white patches of skin), or hyperpigmentation, premature grey hair and impotence. Anybody at any age can become deficient but people may be at an increased risk if they are
- Vegans and vegetarians
- Over 60
- Have eating disorders such as anorexia or bulimia
- Take antacids or diabetes related drugs that may interfere with B12 absorption
- Have a history of alcoholism
- Have a family history of pernicious anaemia
- Are diagnosed with anaemia
- Have Crohns disease, irritable bowel or any disease causing malaborption of nutrients
- Have an autoimmune disease, type 1 diabetes, SLE, Addisons disease
- Women with a history of infertility or multiple miscarriages
- Infants born to women or breast fed by women who are already deficient or at risk of B12 deficiency
All forms of B12 are stable when protected from light. Light exposure cleaves the cyanide with the production of hydroxycobalamin. The B12s have an optimal stability at a PH4.00-4.5, even at higher temperatures. In the presence of acid or alkaline mediator the presence of reducing agents such as ascorbic acid the vitamin is destroyed to a greater extent. It is therefore advisable that Vitamin B12 is not taken with fruit juice.
Ingredients: (Each capsule contains)
Methylcobalamin (Vitamin B12) 1000mcg ( 1mg ) Other ingredients; Cellulose, Hydroxypropyl Methylcellulose (capsule)